Customized Services for Animal Model of Cysticercus cellulosae Infection
Cysticercus cellulosae is the larvae of the tapeworm, a common food-borne zoonotic parasite. Humans are the end hosts of the pig tapeworm, and intermediate hosts include dogs, cats, and humans in addition to pigs. The meat of animals discarded every year due to contamination by cysticerci causes huge losses to the rural economy.
Cysticercus cellulosae are mainly parasitized in the muscles or tissues of pigs. When they are parasitized in the lungs or throat of pigs, they often cause difficulty in breathing and swallowing; if they are parasitized in the brain tissue of pigs, symptoms such as epilepsy or acute encephalitis will occur, and even death will occur. It can also enter the human digestive tract through the food chain and endanger people's health. When people are infected, they often have muscle aches and pains, weak limbs and often feel sleepy. If the parasites are found in the brain, eyes and vocal cords, they can cause neurological symptoms such as blindness and hoarseness.
Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Cysticercus cellulosae. This provides a good model for the morphology, life history and especially the molecular biology of Cysticercus cellulosae and the study of Cysticercoids cellulosae.
Customization Service Options for Animal Models of Cysticercus cellulosae Infection
We can construct a Cysticercus cellulosae model for you in mice, it can be used for scientific research and drug research of Cysticercoids cellulosae. If you want to know more, you are welcome to consult us.
- Mice model of Cysticercus cellulosae
Model animal: KM mice (22-25g)
Parasite source: activated six-hook larvae. The pregnant segments of the patient's pig tapeworm were collected, the eggs were washed off, and then the eggs were incubated to obtain the six-hook larvae.
Reproduction method: injection via tail vein.
Model characteristics: after 2 months, cysticercus larvae were parasitized in the lungs, heart, bite muscle and leg muscles. There are a few eosinophils around the worm body. Cysticerci antigen or antibody in mouse serum can be detected by ELISA method to verify the infection. The degree of infection varies between model animals; different routes of infection such as gavage, intramuscular, intraperitoneal and intravenous injections affect the parasitization site of cysticercus or directly affect whether it can be parasitized. Since the model animals were infected through tail vein injection, which is different from the way of oral infection in humans or pigs, there are differences in the route of circulation of Cysticercus cellulosae in the body, thus causing differences in the parasitization sites of Cysticercus cellulosae.
Application: this model can be used for the research of immunity, pathology, pharmacology, biochemistry, diagnosis, treatment and genetic engineering vaccine of Cysticercoids cellulosae.
Service Details
Delivery content: experiment report and Cysticercus cellulosae animal model
Test fee: please get it through online inquiry.
Service Flow
- Communicate your requirements with us via online inquiry or telephone.
- Communicate the requirements (Number, degree of infection, etc.) of Cysticercus cellulosae animal model customization, sign the contract and pay the deposit.
- Fill out the sample order and send the samples (optional).
- Establish Cysticercus cellulosae animal model and prepare experiment report.
- Delivery of report and animal model.
Our Advantages
- We offer rat models of Cysticercus cellulosae that can be used for scientific research and drug research of Cysticercoids cellulosae. If you have special needs, please consult us for customization.
- Our professional technicians have extensive experience in parasite animal model development.
- Advanced technology platform, scientific management system, and standard R&D procedures.
- In addition to Cysticercus cellulosae animal model customization service, we also provide Cysticercus cellulosae identification (Stool testing (eggs or nodules), biopsy of subcutaneous nodules/muscles, intradermal testing, indirect hemagglutination, enzyme-linked immunosorbent assay (ELISA), etc.) and in vitro culture services.
- The project cycle time is short and the price is competitive.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
