Multi-omics Service for Plant Virus
Plant viruses must live parasitically in the host cell, specificity, a virus can only infest a certain kind or some plants. However, there are a few that cause widespread damage, such as the tobacco mosaic virus and cucumber mosaic virus. Generally, plant viruses are active only in the living body of the host, only a few plant viruses can remain active in the remains of the diseased plant, and a few plant viruses can survive or proliferate in the living body of insects. Plant viruses are spread by a variety of means. In addition to virulent propagation materials such as scions, bulbs, tubers, and tubers, plant viruses are also spread by insects, mites, soil fungi, nematodes, and other vectors. In addition, pollen and seeds can spread the virus in melon and bean plants, and grafting can spread the virus in fruit trees. Therefore, the virus diseases of vegetables in the hot season are very much, which is still a worldwide plant protection problem. There are many types of viruses on plants, and plants often have a mixture of multiple viruses infected. The types of symptoms after infestation are generally foliar, yellowing, necrotic, and deformed. The mechanism of action of existing antiviral agents is mainly to inhibit virus infestation, inhibit virus proliferation, and induce plant resistance, and the control of virus diseases is mainly reflected in early prevention.
Ace Therapeutics provides multi-omics services for plant viruses, including but not limited to Meta-virome and proteomics. helps you to study from multiple dimensions including the comparison of the structure and function of the genome of plant viruses, differences in viral expression, etc. It can help us to study diseases and viruses that have not yet been explained, so that we can prioritize effective therapeutic strategies to suppress viruses and their transmission, rationalize epidemiological trends, and effectively control viruses.
Plant viruses that we can service include, but are not limited to, potato virus Y (PVY), potato virus X (PVX), cauliflower mosaic virus (CaMV), African cassava mosaic virus (ACMV), plum pox virus ( PPV), brome mosaic virus (BMV), tobacco mosaic virus (TMV), tomato spotted wilt virus (TSWV), tomato yellow leaf curl virus (TYLCV).
Multi-Omics Service Options for Plant Viruses
1. Meta-virome
We provide mata-virome sequencing and analysis services for many plant viruses.
Standard analysis content
| Removal of host sequences |
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| Single sample viral sequence assembly |
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| Virus community structure composition |
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| Virus community structure diversity analysis |
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| Analysis of inter-group variation in virus community structure |
1) Species abundance-based analysis (downscaling/clustering/Venn diagram and petal plot analysis)
2) Inter-group species analysis (Metastat/STAMP/LEfSe analysis)
3) Virus community member association network analysis
4) Intra-group core species analysis |
| Phage host prediction |
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| Viral sequence de novo prediction |
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| Viral ORFs prediction |
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| Viral functional gene annotation |
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| Viral community functional diversity analysis |
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| Differential functional analysis of viruses between groups |
1) Difference detection
2) Dimensional reduction analysis of functional abundance
3) Functional abundance clustering analysis
4) LEfSe analysis to resolve differential function biomarker |
Note: Please contact sales or technical support for personalized analysis and multi-omics association analysis.
2. Proteomics
Viruses are parasitic in host cells and need to constantly adapt and change their host environment. They are able to encode a variety of multifunctional proteins that interact with host proteins in a series of interactions to accomplish various viral functions. We rely on mass spectrometry to provide proteomics f analysis of plant viruses, which not only promotes the continuous progress of viral proteomics research but also accelerates the identification of virus-related host proteins.
Technology selections
- Quantitative proteomics (TMT, SILAC, and off-label quantification)
- Targeted quantification (PRM, SRM, and SureQuant)
- Post-Translational Modification (PTM)
Note: In addition, there are other services available for you to choose from, please consult us for details. Viral multi-omics provides new ideas for disease treatment, as well as a foundation for studies such as viral surveillance and resistance to existing antiviral drugs for viruses.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
